How brain circuitry regulating specific behaviors emerges from development remains unknown. Research in the Corbin Laboratory of Developmental Neuroscience is directed toward addressing how genetic embryonic neurodevelopmental programs pattern development of circuitry of the limbic system: an interconnected set of brain structures that includes the olfactory system, amygdala, and hypothalamus. Moreover, we are interested in the consequences of when these processes go awry, resulting in neurodevelopmental disorders such as autism spectrum disorders.
Using the mouse as a model, we employ a combination of techniques including embryology, genomic profiling, state of the art circuit tracing and manipulation, and behavior. The goal of our studies is not only to gain greater insight into the neurotypical developing brain, but address core behavioral deficits in prevalent human neurodevelopmental disorders. We are also always looking for highly motivated inquisitive individuals to join our diverse team of researchers, including hosting thesis students from University of Maryland-College Park, Georgetown University, and George Washington University.
Follow us on Twitter for more updates on our projects @TheCorbinLab!